This paper presents the computational study results of the ascending gas-liquid flow local structure in a vertical pipe. The mathematical model is based on the use of two-fluid Eulerian approach taking into account the inverse influence of bubbles on averaged characteristics and turbulence of the carrying phase. The equations conservation of mass and momentum quantity of motion in the form of Navier-Stokes equations averaged over Reynolds for each phase are written down. For turbulent stresses the relations under the assumption of the Boussinesq hypothesis are written.